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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3aab19e442baa2039b2554095b960a9edf1fd0581a814f2aa66441d5f02d7a05' 
  AND token = 'vZC4RoPjwurVgwJdOE2rhXAdL3tugWQw5msX3l/+RoE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}