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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3091058907d76516427dc527a6aca42e09f46d395099a5324f1ce9ca20c2a87c' 
  AND token = 'sp0404RWYm/cVpURS7qxXlTzyC/gX0PgybwGTGjRKRM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}