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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '20c5f4749f0bfb1996c2e50be9551414d889287b83f55ae9b7b069f560a38278' 
  AND token = 's/2zEfeyKCNdor5eZMF3TN2PjygCS2nmcTZW2DxqcYQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}