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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6b111a6690755e497454f59ddd7d50f85190036dc06e6f5fc6bcae8b8b4769b8' 
  AND token = 'BzD8fKFDzLVD9wSF/b+5XVaiDpY6UqCETUSIeUCDzoQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}