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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8afa78b5e07e582f1e9ecf64ed909cb898e9286a938a0a76af90c0bb2a2e0669' 
  AND token = 'nCDK68sLIYRUiEbUsQwxqWecNdRUEJX3NaBkwTJLtjM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}