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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b8848f65c75267cac0d27a4409bdb0e87e6ef30c98836afaa70bd757c0fee8a3' 
  AND token = 'SRjR5sAUB4aUB7M/hUDCuPIu3cuDOUFWgaZiRPlYpPs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}