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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '72e5608a7258992315b90a842a5b0228038915a69313b36e6159e4b337b4c64c' 
  AND token = 'HLmV28XO05n+bZe0vOLRV8Bpm5/CN18/zvzcmK6nGeQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}