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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '73b53085feee58a56318e318aac1883f2b8c4a172726897b0c2f138e21a320fa' 
  AND token = 'M71xCyVYx+xSZFS0VJyGgGjkgPHp8RdULpSWTFL5ZgQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}