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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5a214bb05e54d21878c53495da37693a38b24ae2bbe195e22c87dc5815376ae1' 
  AND token = 'nQML2BaFY3VeAvLLPU5kwLSZTn73zIG4hlT8KEgPQKg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}