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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a0653d6a269dfd662387cdd749d5e2031f48d8a1e220db1e4a4b26837e9c8b8a' 
  AND token = 'ys0hCzmqKmk80fx7h5gxhDTI3dZpKZOnzqPfNMNnl3M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}