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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '425a303043a271e8faa3a40dad5a179e37faf0996428cbf93168b35e490ab719' 
  AND token = 'a0j6wja7URXk7FxIjN+RrrZXg0mh1qUjpM2AB6prl9o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}