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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a1cae1bc2d4eb1bf2973419e9c88d1a7264886590f54f796bfbe4f7b08feca23' 
  AND token = '7pznukmRgoAcLcNprDxVjKRBaQHy7lsnsQGE4aAtzrw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}