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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cf2e218b0d053e33c6922d35673fbd07f77ab981ae00c7da4d7b1505a3e45f7c' 
  AND token = '7gczZMRcqjRcsLZXlqvQFRGDX5/yanmFb4SkiUJX9Zk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00055

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}