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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cce78378f1d61303f5b610825368a6c4166b866353c1458561e8468600ff235e' 
  AND token = 'KRAEmRxauBXB+2vu8U91gI9aOSFu20i7Dp3zI/Irpwc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}