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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3dff9626a36d56ec9c666b9c2e6226dcd96fa1ec4e5cc7ada7115a59a79d07ac' 
  AND token = '7SxLDJ5pRxLI4GAEdZgem1s8ERPj8UiWiqXfQoHpbEA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}