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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd40a57d5eec35a2901be09dcb74ada97263262dbfd5d974ac56b713c1f211f0e' 
  AND token = 'YPJbN7y110HLMiUhUd33gVACUtAaSkxL0vlmfMYEA48=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}