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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd7d8d837203d44c7fc654348118c2d4af165d0114a95b7742db9fb4781b8c491' 
  AND token = '1Es2AKEZhXI9HsEYyAPKXdZNj4lVzT8dngPOA8PjfX0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}