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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'aad21f395ea471b2c5d99580242fb314596c28d91533182a66794e346c786e5c' 
  AND token = 'EUR7RMRcnI7zzM6t68Gmomb1N/zzW1PM0PUC+s34MAA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}