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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2ff2969388ac47858999649c4c796a8eed75bafb46661016667765004e8600ad' 
  AND token = 'pKGK4d3A9ZsQVCWf/LJ6tD0L4sfXkfVKCkApYbEOHd0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}