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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1f2981af9b32aa1a3525635f13559f64d864305725c7ea996cbd1a87580d334e' 
  AND token = 'fXt86zcDWKmnU4c+bRfZijkVzWswUwx/4240P0hpkpM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}