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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5e1c5f60eca0af023f7a9a9c3bedd2c265abff6d0a637739fe60d938909b91fb' 
  AND token = 'Sd2748YjhRuCzE8qnbW4bl4HRKOthaxHDRE5Dwy9lrU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}