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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ad1846d7e820111a5666c716eb02e5d82f8be1cc4e7b58868fdcfc4e89a075af' 
  AND token = '3eeoMFmqirqpA1fHRmXrF/ZN/6jEXg4SUVMoibasrAg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}