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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8d9cde6e8c6b29eea3430fac33bc1020a318bf5de70d22930e9fe1706239e714' 
  AND token = 'R/97/nnXlxAcZsIapCEUvF9r4wpNzsx1IAPgy2Zy34s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}