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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0617c378b56388c44d6d27e13474d8f1d96c08d5b8213105a0653d0f54321cd4' 
  AND token = 'tEftcBfj5uOZ3RHjWkCmIxLg03rwc9x+E4wmQiCuZrc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}