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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4ea96f422c2cfd03cadf7617a6bf2c407851001636dc1dc1044ed4315c3e1d44' 
  AND token = 'zwdL0hCq8BqMhjUGU/4MdyBz8BuNmdnYVm+jFTNOAXU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}