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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '00fa6263ad23f575c0a626efdf5b1c40072aba8ee478a5c150addf455cfde303' 
  AND token = 'GXYy1K9rUApGpABorFY3xdoQGCJxYGq/BFDrA3My2V4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}