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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '412086aac11b1b26de5c505ec38ce409b0d8f3c3ee26243cf6307fdfb6f39f60' 
  AND token = '+OgY2R6o0wW8z37TCAaEDSTq9alQQjlu/AwzODTy4rE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}