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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a49f8b5e1b8c4189873fb603b88b4860d6a76b604059e3df8a6befd498d30d4c' 
  AND token = 'MB9auc6R8RfZExwOwlzaATsfrsRRBB69dSewQ56BycY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}