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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b8b8695688b203be5f98f33f07a4aeaed7baa08a7c768592a4f1a473a77fb462' 
  AND token = 'gugNywpX1f7LWyYekJZhnl8QnwEdM+tkT2yaGGUzko8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}