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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9c6b7ca63699d341a465ac4824bdc90f1649ab2b5ee96ae921a919b63e98f9a9' 
  AND token = 'd6acHEoun5Y2eqN1//MBeAnsu8ZzdF6lNV7vF/m4ZZo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}