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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd59e96a8ff1023b0b7576be2411857715521a99c5dfcf41721d9000c108676f3' 
  AND token = 'JIz71QGHqtEZ59cEPTo0Pbph1fpkzTxleb23Ao/a0z0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}