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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a2ef055a801ee6ca00dcca2dfb76f8f441e00421bf8ac13f921ef45a36ca068c' 
  AND token = 'sIo75oIWvB8q6lfaiFu3HRBTweihQzceF8MtH/lk3Tk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}