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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '67e1d8804fea39aad7f1d1b9f8b8ea1b896e350c722944f4ab04a920996f3ba4' 
  AND token = 'SFmx5wIUYpIcuUv1Hlv86cmMoOyO+7ql2O+b/TF9KfM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}