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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4674895c226dbb8f0627b3c004f33a586b90397a1dc2f41cfffa6958a1343036' 
  AND token = 'bLN4faGhAOX1N6innYavi9PTUnTSAPYHVBzFIjfMcco=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}