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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e6c4c0a97d9a7969fa69d6085b1f5b2019833011f73226cab5eff26ad2b95a12' 
  AND token = 'gyrSPbPBRsYUSPHM5IUXcGnUhfQgAdEHC2wwmmbhXnk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}