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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2bbf41d0c2b23b7f59e5c1c410c4033db5d4a6adc098cd875fd1afcbe5610a60' 
  AND token = 'y0wqh2HEW+n2aZg7032mHp0D5P48Bv/+xp0X5gez68I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}