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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1aa1266d7c620fd936cc28a5c7a89ee41fc45fbe8ebb1d67d8117bfb682b1403' 
  AND token = 'fKbzH/Wu1QNTwVoEezxsYRYwdjpPmkQRIDIybtcLeSo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}