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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b34d39446ba322f45e2a486c8429eb30b6109e2d0456ae561f95a746badd9d04' 
  AND token = 'ku/oToS4uG4Ba/sXMDEk2fFBlOu77VhhnV2Fh7+ep4I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}