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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1b72e46a407454d560837d03b5b92e964fcd6c774988de50049c4aa7c160d358' 
  AND token = '/8UtvWUqbRSmATtMIMbKbt2cuIKX0Waran52bK2Hv+Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}