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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '786a695dfc9ff57044dd3ddeabdf1a3d5dce4c3a56b308d0486e540f5b9384fb' 
  AND token = 'kcGSKC4EEDrLDYotB8OQbUYc1Hz80I4bvW+zpcZHjX4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}