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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '478d7ef8eaa1f41f6d37a42d80352de5ab50cd3c8391122eec60809f5ec5d510' 
  AND token = 'JbvgiYsTQkUdhPr/08eSYyozES4WAQ9miiXkwqAmNtw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}