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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '29bf469db7ad6ef103afc4f241238b1b104d5e7cda71ea8349ed90140145bb5e' 
  AND token = 'oJEDaSLL6wZHLMVm4fwUwbC/4e8D15nar3q45rSX4Ws=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}