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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6c975f6f1f0f1cc02cf31a2b58a853c8c637228bcc0c13dbb74e347c8125d017' 
  AND token = 'dUC6bC/iufc/lxp8UEoSBzCPA/Ph5LFDL3WDHltDQeA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}