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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5df410ba087947c7bce0a838216a9595f4423dfb01d2aea3b947bd05ffb744bc' 
  AND token = 'SLjTgN83wotMRfYdHVmJnLQZ5tQZwaUBWFfHzmtOfdE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}