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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6c5bd26280c753966c0054612a422564890e55690a2bde8224ff0d2ee34ce327' 
  AND token = 'msAzJklZlQk1WtvV22EVHv5WRxhoIKJDUi9qtsrrVzM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}