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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '49780e0aa0aedce24536c75320a4bd9c532829a41b88a6b58bcd49eddc56a5da' 
  AND token = '2KypVfMUZcJLaQROva4FA3IQnHrh9z6zg1Tg9eUcMmw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}