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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '710046dd13c7b1f7b5fb6f00d8af7759988453a8b5f0a5df10e8dfa60b62be69' 
  AND token = 'RHM6u2HO2qu/WqC0TyygrfXqbq/K8uIKkNM+fqQmDVM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}