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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2a669710f61040246b017221b56cd55c8a0dbaac19e04cc42a3df7eee965b066' 
  AND token = 'XDzlYXo818XhOmUiYJtesiLtbHkir7sj3ztlegiB5JU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}