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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2c60f362c6cebf4c99a117a2715d187532cf1f933598dea9837e09587d37db25' 
  AND token = 'E8AMmnyqRA7fnt/h6u1Vv27L4asbG/mC59LhAwZ7TC0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}