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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd9753f3a75df20a28bb58e54a60fd6b791c9d5648c32d5e222afd2328df4990d' 
  AND token = '1dPsyzXbQJ9QpD1tZxAg5GxCCfdLHEAX/evVIn+3gaA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}